A pandemic is an epidemic of a disease that has spread across a large region, usually crossing international boundaries and affecting a large number of people. For many years the most common disease referenced as a pandemic is an influenza pandemic. However, pandemics can happen with other types of diseases as well. The information provided here, while often referencing an influenza pandemic, is generally applicable to all types of pandemic outbreaks. Key to preparing for and responding to a pandemic is paying close attention to advisories and guidance from public health agencies, such as the Centers for Disease Control and Prevention, the World Health Organization, the Florida Department of Health, as well as the STOF Health and Human Services Department.